The cyclodextrin inclusion complex-containing biodegradable polymeric systems as drug carrier
نویسندگان
چکیده
منابع مشابه
Sulfisoxazole/cyclodextrin inclusion complex incorporated in electrospun hydroxypropyl cellulose nanofibers as drug delivery system.
Herein, hydroxypropyl-beta-cyclodextrin (HPβCD) inclusion complex (IC) of a hydrophobic drug, sulfisoxazole (SFS) was incorporated in hydroxypropyl cellulose (HPC) nanofibers (HPC/SFS/HPβCD-IC-NF) via electrospinning. SFS/HPβCD-IC was characterized by DSC to investigate the formation of inclusion complex and the stoichiometry of the complex was determined by Job's plot. Modeling studies were al...
متن کاملEnhanced thermal stability of eugenol by cyclodextrin inclusion complex encapsulated in electrospun polymeric nanofibers.
Polyvinyl alcohol (PVA) nanofibers encapsulating eugenol (EG)/cyclodextrin (CD) inclusion complexes (IC) (EG/CD-IC) were produced via electrospinning technique in order to achieve high thermal stability and slow release of EG. In order to find out the most favorable CD type for the stabilization of EG, three types of native cyclodextrins (α-CD, β-CD, and γ-CD) were used for the formation of EG/...
متن کاملPhotoresponsive coumarin-stabilized polymeric nanoparticles as a detectable drug carrier.
The ability to create aqueous suspended stable nanoparticles of the hydrophobic homopolymer poly(ϵ-caprolactone) end-functionalized with coumarin moieties (CPCL) is demonstrated. Nanoparticles of CPCL are prepared in a continuous manner using nanoprecipitation. The resulting nanoparticles are spherical in morphology, about 40 nm in diameter, and possess a narrow size distribution and excellent ...
متن کاملΒ-cyclodextrin Inclusion Complex of Curcumin
Formation of inclusion complex of curcumin with β-cyclodextrin ( β-CD) has been characterized by absorption and fluorescence spectroscopy. From temperature-dependent fluorescence measurements, the thermodynamic parameters ∆H and ∆S, for the complexation were estimated. Kinetics of binding was studied by stopped flow technique, from which the binding constants for inclusion complex was estimated...
متن کاملPreparation and Evaluation of Inclusion Complex of the Lipid Lowering Drug Lovastatin with β-Cyclodextrin
Several attempts have been made to improve the solubility of water insoluble drugs. Over the years, inclusion complexation of drugs with β-cyclodextrin has emerged as a viable attempt to improve the dissolution of water insoluble drugs. The aim of the present work was to improve the dissolution rate of lovastatin, a water insoluble drug, by inclusion complexation with β-cyclodextrin. The stoich...
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ژورنال
عنوان ژورنال: Journal of Science and Technology Issue on Information and Communications Technology
سال: 2019
ISSN: 1859-1531
DOI: 10.31130/jst-ud2019-084e